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PMID 7588385

It can promote tissue repair, reduces inflammation, enhances angiogenesis (new blood vessel formation), and remains stable in gastric juice enabling effective oral administration

J Cereb Blood Flow Metab 2007

The methyl group transfer to the target molecule transforms SAM into S-adenosylhomocysteine (SAH), which subsequently undergoes a deadenylation reaction to yield homocysteine (23)

Grapefruit juice is a highly notorious and prototypical inhibitor of this metabolic pathway and its ability to wreak havoc with drug concentrations is well-documented