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Description

Higher levels of this enzyme sensitize senescent cells to ferroptosis, while removing or inhibiting acid ceramidase makes cells more resilient

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(2024b)

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doi: 10.2119/molmed.2014.00032 55 WoodSMGleadleJMPughCWHankinsonORatcliffePJ

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Here we identified Lys105 of ScGrx7 and Lys26 of PfGrx as a dual activator for the catalytic cysteine residue and GSH

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To overcome these limitations of GSH, pro-GSH molecules could be used to restore or increase GSH levels [25]

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