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This leads to enhanced conformational changes in Pin1 and in turn changes in p47 phox conformation, which reveals additional phosphorylation sites on p47 phox for phosphorylation (Dang et al., 2006

High-content microscopy Similar to previous studies, high-content microscopy was performed as reported by Hernandez et al

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Balancing sedimentation-induced gravity by centrifugation (horizontally at 30 rpm for 24 h) was carried out to generate the simulated microgravity 42

Results: 164 out of 400 patients completed the survey (41%) with a mean age of 64 10 years, 54% male and 75% non-Hispanic white