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Description

10.1007/s12576-013-0279-2 222

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Reported laboratory work covers its involvement in signalling pathways including sirtuins, poly(ADP-ribose) polymerases (PARPs) and cyclic ADP-ribose-generating enzymes linked to DNA repair, chromatin regulation and calcium signalling

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However, the pharmacokinetic interaction of NS with conventional drugs raises some concerns which need addressing

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