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monitor patient closely

Front Plant Sci 6:723737 Parisy V, Poinssot B, Owsianowski L, Buchala A, Glazebrook J, Mauch F (2007) Identification of PAD2 as a -glutamylcysteine synthetase highlights the importance of glutathione in disease resistance of Arabidopsis

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While it is uncertain whether these alterations also involve modified incretin responses, within the framework of obesity, MetS and the use of hydrochlorothiazide for treating hypertension associated with these conditions, these findings suggest an intriguing hypothesis: that overweight or overnutrition might amplify the metabolic effects of these diuretics by inhibiting NCC and/or other targets in -cells and in metabolically active tissues but independently of insulin secretion

2004;6(6):R713R722.