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Below, we review the published evidence regarding TRPM2s involvement in the pathophysiological mechanisms of neurological diseases, with the experimental models employed and the key inflammation-related outcomes presented in Table 1

Y391K LC H3K4M: CoREST1, bound to Y391K LSD1 (black), adopts a distinct conformation compared to CoREST1 bound to WT LSD1 (blue), shifting downward towards H3K4M

Biomedicine Pharmacotherapy 131 , 110698 (2020)

Organs with an epithelial lining can be directly affected, leading to respiratory distress syndrome, colitis, pancreatic injury, liver dysfunction, and other complications [27, 51, 55]

approved date July 2, 2022) following the Guidelines for the Care and Use of Animals