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To obtain acceptable articles up to October 2022, a thorough search was conducted in databases including PubMed, ISI Web of Science, the Cochrane Library, and Scopus

Am J Physiol Endocrinol Metab (2005) 289:E27887

Why it matters: For patients with chronic joint pain, tendonitis, gut inflammation, or post-surgical inflammation, this means less swelling, better circulation, and faster repair

Only a small part of patients experienced a flare after the initial improvement (103, 104)

Yet, despite its importance, many of us may not fully understand how long-term supplementation of this powerful compound can impact our health