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J.et al (2019)

The permeability against small substances of the intestinal epithelium depends on the regulation of intercellular tight junctions (TJ)

5, we showed that at various concentrations (5, 10, 25, 50, 100, 200 M), 4-OXO-DHA dose-dependently inhibited NF-B-DNA binding

This process is known as the negative feedback loop