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Addressing this question will require conditional genetic models and in vivo imaging approaches to clarify causal interactions across different stages, brain regions, and cell types

Similarly, other ligands (triphenylphosphonium, AS1) and gH625 (viral derived peptide for effective delivery) have already been shown to preferentially target astrocytes ( Microglia, the brain's resident immune cells, eliminates dead cells, and debris, secretes neurotrophic factors, and contributes to the overall homeostasis of the CNS (80)

Methods to prevent excessive oxidative harm to healthy tissues including targeted administration of pro-oxidant agents, antibodydrug conjugates, and prodrugs activated in tumour -specific environments [237]

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doi: 10.1007/s10571-023-01388-8 36 WangBWangYZhangJHuCJiangJLiYet al