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Description

5-Amino-1MQ presents a narrower dosing window due to its potent NNMT inhibition

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Key takeaway: Suggests possible relevance for joint and connective tissue research

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(Giuliante et al., 2015) reported pronounced elevation of NNMT protein expression, gene expression, and enzyme activity in the adipose tissue of rats afflicted with MetS

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Daily NNMT inhibitor effects on body weight measures in DIO mice was analyzed using a repeated measures two-way ANOVA with Sidak's multiple comparison posthoc test

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Results indicated that rats receiving AOD 9604 experienced body weight reductions by greater than 50 percent compared with the control group

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