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Biotransformations Leading to Toxic Metabolites: Chemical Aspects ScienceDirect The metabolic pathways of acetaminophen (APAP) in the human body. The Download Scientific Diagram Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors Acetaminophen (Paracetamol) Poisoning RECAPEM Alcohol and paracetamol are both processed through the liver. Paracetamol can form a toxic metabolite called NAPQI, which the body usually neutralises safely. But factors like heavy alcohol use, repeated dosing, fasting
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