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however, treatment with 100 mg/kg of berberine mitigated this upregulation

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Antioxidants are the eliminators and detoxifiers of the free radicals in your body

The goal is the minimum effective dose, not the maximum tolerable dose

Similarly, in this study, the addition of GSH caused auxin input vector AUX related genes to be downregulated, transcription suppressor Aux/IAA to be activated, related genes to be upregulated, and auxin response factor ARF to be inhibited, thus inhibiting auxin signal transduction and improving cadmium tolerance of potato