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With cobalamin injections, neurologic symptoms may worsen transiently and then subside over weeks to months (Healton et al ., 1991)

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Furthermore, fungal infection generally presents more difficult therapeutic problems than bacterial infections because fungi are eukaryotes cells so compounds that can inhibit fungal growth have a higher side effect on host eukaryotic cells than antibiotics which target prokaryotic bacterial cells (Perfect 2012)

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