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In 2011, Kakkar and Kaur introduced spanlastics, a non-immunogenic, biodegradable system that delivers medications via various routes, including oral, topical, nasal, and transdermal methods 29

Although glucose is the principal energy fuel of the brain in normal conditions, lactate can be an alternative source during hypoglycemia and because of mitochondrial shifts in redox state or ischemia

This process is critical during exercise, when fat becomes a key fuel source

As we age, the fat tissue sinks and tends to disappear, exposing the blood vessels and causing dark eye circles