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Lin, J.E

Oxidant mechanisms in childhood obesity: the link between inflammation and oxidative stress

Reactive oxygen species result in the formation of free radicals, highly reactive molecules which cause cellular and tissue damage in the form of oxidative stress

This prevents the hydroxylation of HIF-1, thereby blocking its recognition and subsequent degradation by the VHL-mediated proteasomal system [96, 97]

Abstract Birth asphyxia and its main sequel, hypoxic-ischemic encephalopathy, are one of the leading causes of childrens deaths worldwide and can potentially worsen the quality of life in subsequent years