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Emma Arnal, Cristina Peris-Martnez, Jose Luis Menezo, Siv Johnsen-Soriano and Francisco Javier Romero Invest

References: Acharya Dahal R et al (2014): Computational and biochemical docking of the irreversible cocaine analog RTI 82 directly demonstrates ligand positioning in the dopamine transporter central substrate-binding site

The SLC7A11/GPX4 axis, serving as a pivotal inhibitory pathway in the orchestration of ferroptosis, has garnered substantial attention

Side effect Liraglutide can cause similar GI side effects to semaglutide, including constipation, diarrhea, nausea, and vomiting

Therapeutically, small-molecule antioxidants and nutraceuticals laid the groundwork, but their limited organelle specificity and bioavailability have driven the development of mechanism-based approaches