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For example, the simulated (lines) and measured (dots) data of midazolam and its metabolites 1-hydroxymidazolam (OH-MDZ) and 1-hydroxymidazolam glucuronide (OH-MDZ-G) in plasma are shown in Figure 3D, while simulations and data of all other compounds are provided in the Supplementary Figures S1, S2, Supplementary Tables S3S20

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