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Description

HDAC class I inhibitor domatinostat sensitizes pancreatic cancer to chemotherapy by targeting cancer stem cell compartment via FOXM1 modulation

(1) Research has posited that this fragment encompasses GHs primary lipolytic domain

It suggested that the oxidation of tyrosine was light-driven

We then compared the proteolytic fingerprints of lysates from cells grown under oxidative stress to those grown under nave conditions, and examined the effect that oxidative conditions have on the proteolytic capacity of the 20S proteasome