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The carnitine system and cancer metabolic plasticity Cell Death & Disease Frontiers Exogenous L carnitine Administration Ameliorates the Adverse Effects of Heat Stress on Testicular Hemodynamics, Echotexture, and Total Antioxidant Capacity in Rams Limosilactobacillus reuteri promotes the expression and secretion of enteroendocrine and enterocytederived hormones Di Rienzi 2025 The FASEB Journal Wiley Online Library Evaluation of L Carnitine Potential in Improvement of Male Fertility PMC Frontiers Morinda officinalis oligosaccharides improves sperm motility via the gut microbiota and the IGF 1 PI3K mTOR signaling pathway

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HIF-1 is also known to promote mitochondrial-selective autophagy and thus lower the mitochondrial mass, which suppresses the oxidation of both glucose and fatty acids and decreases mitochondrial ROS production under hypoxic conditions (63)