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doi: 10.1007/s00424-005-1428-0 112 KriajD.HuangW.FurukawaT.PunzoC.XingW

For example, a micelle-in-hydrogel formulation containing only 0.075% hydrocortisone achieved a 9.2-fold increase in skin flux and a 50-fold improvement in cumulative permeation compared to a 1% commercial cream, revealing the advantage of follicular targeting in transdermal drug delivery (Yuan et al., 2020)