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In addition, several studies demonstrated that increased dietary intake of DHA prevents vascular pathology through inhibition of ASM in the retina, leading to an inhibition of retinal endothelial cell activation by inflammatory cytokines and reducing pathological retinal angiogenesis (Busik et al., Sphingolipids Diabetes has also been shown to affect sphingolipid metabolism (Fox et al., 2011)

There is a significant association between the decrease in platelet count with the duration of phototherapy and lower gestational age in the neonate (Sarkar et al., 2021)

Kojic Acid: Known for its skin lightening effects, Kojic Acid helps to fade hyperpigmentation, age spots, and sun damage, revealing a more luminous and even-toned complexion

Curcumin (direct inhibitor of STAT3 and NF-kB activation) 281,282,283 is studied in the combination with PDT and/or PTT/hyperthemia 256,284,285 Curcumin also decreases HSP efficiency in cancer cells 286 (including HSP-70) 256 , effectively suppressing the hypoxic phenotype in tumor tissues and activating the anti-tumor immune system 287,288