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Spatial and temporal expression of zebrafish glutathione peroxidase 4 a and b genes during early embryo development

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The trafficking itinerary that moves GLUT4 to and from the cell surface is complex, involving a series of overlapping processes that (1) render GLUT4 insulin responsive by sorting it into GSVs, and (2) promote GLUT4 accumulation at the PM in adipocytes or sarcolemma and t-tubules in muscle in response to insulin signalling (Figure 3)

21 Moreover, extracellular lactate-induced H3K18la in T helper 17 (Th17) cells, a subset of CD4 + T helper cells secreting IL-17, contributes to transforming pro-inflammatory T cells into Treg cells