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Regulatory mechanisms of hypoxia-inducible factor 1 activity: Two decades of knowledge

Mitochondrial membranes, like cell membranes, are rich in polyunsaturated fatty acids (PUFAs) and are also susceptible to high levels of ROS [83]

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The epithelialmesenchymal transition is governed by biochemical changes that allow specific epithelial cells to adopt a mesenchymal phenotype, acquire invasive capabilities, disseminate throughout the body, and resist stress (Ye and Weinberg 2015)