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Finally, the distribution of senescent cells varies in different tissues and organs

The Eph receptors, the largest family of receptor tyrosine kinases in the mammalian genome, affect inflammation and fibrosis in other model systems, and we have shown that EphA2 deletion reduces atherosclerosis despite increasing plasma cholesterol levels

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[DOI] [PubMed] [Google Scholar] 91.Keller J., Ringseis R., Koc A., Lukas I., Kluge H., Eder K

We suggest that R130 plays an important role in stabilization of this transition state