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For most people, Botox injections are not painful, and patients dont generally require any topical anesthetic prior to the procedure

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Muscles take on a harder, more striated appearance

As mentioned above, when stacked with ipamorelin, the two peptides theoretically work together to quickly surge GH, then keep levels high for an extended time

5 Botulinum toxin, with doses as high as 100 units, has also been used off-label to reduce erythema and flushing given its anti-inflammatory and inhibitory effects on neurotransmitters and neuropeptides and a resulting hypothetical effect on vasomotor tone