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Although many studies reported promising results with minimal toxicity or side effects, there were study limitations such as small sample sizes, variability in formulations, and the pharmacokinetic properties of curcumin

ACS Omega 7:1966519675 Ali AA, Khalil MG, Abd El-Latif DM, Okda T, Abdelaziz AI, Kamal MM, Wahid A (2022) The influence of vinpocetine alone or in combination with Epigallocatechin-3-gallate, Coenzyme COQ10, Vitamin E and Selenium as a potential neuroprotective combination against aluminium-induced Alzheimers disease in Wistar Albino Rats

Supplementary tablets can be taken to account for a lack of Vitamin B12 in the diet

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