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This research helps to rationally design the next-generation analgesics, and is expected to reduce the side effects of opioids without affecting their analgesic effect, or even enhance the analgesic effects.

One common ingredient found in these injections is phosphatidylcholine (PC), which is a naturally occurring substance in the body

When in abundant supply, glutathione inhibits the gamma-glutamyl cysteine synthetase enzyme

To test that hypothesis we used phallodin, the toxin found in cap mushroom, known to bind specifically at the interface of F-actin subunits (Figure 5)

Peptides and antibiotic therapy: Advances in design and delivery