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doi: 10.1158/0008-5472.CAN-13-1641

It is especially helpful in individuals who suffer from Crohns Disease, Ulcerative Colitis, Celiac Disease, or those who suffer from frequent Staph (bacterial) or Candida infections (fungal)

Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to regularly evaluate renal function

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During this process, tumor cells undergo a transformation from an epithelial phenotype to a more aggressive mesenchymal phenotype, enhancing the ability to evade the effects of the drug and promote survival