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Moreover, TMZ-mediated O6-methyl (O 6 -Me) guanine damage was shown to trigger an elevation in MMR, mediated by MLH1 and DNA MMR protein MSH2 (MSH2)

Evaluation of mitochondria targeting intranasal compounds To compile the list of intranasal compounds in Table 1, we designed and used a structured data abstraction format to ensure consistency in appraising each intranasal drug

Nordhoff A, Tziatzios C, van den Broek JA

Results indicate that without a control agent, M2 macrophages proliferate, escalating fibrotic tissue formation

NF-B signaling in astrocytes modulates brain inflammation and neuronal injury following sequential exposure to manganese and MPTP during development and aging