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Ferroptosis can therefore be induced by depriving cells of the sulfur-containing GSH precursor, cysteine, via inhibition of the system x c cystine/glutamate antiporter (e.g., using small molecules of the erastin family), or by direct inhibition of GPX4 itself (Forcina & Dixon, 2019)

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The recommended daily intake for adults varies depending on age and gender: 35 mg for men and 25 mg for women aged 50 years or younger, and 30 mg and 20 mg, respectively for older men and women ( Chromium deficiency may present as peripheral neuropathy, insulin resistance, and weight loss