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Currently, no specific laboratory monitoring is required, though tracking inflammatory markers can provide objective evidence of therapeutic effect

Tirzepatide : SURPASS trials showed HbA1c reductions of up to 2.58% (15 mg) with 52% achieving normal HbA1c below 5.7%

This type of therapy is widely used in cancer research and could be investigated as a senolytic approach for chronic diseases

Their research showed that senescent liver cancer cells in mice secreted SASP factors, including the chemokine CCL2, which triggered localized inflammation within the tumor [40]