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Cohen JC, Boerwinkle E, Mosley TH Jr, Hobbs HH

10.1038/nrc2442

Third, the 70% of features that contributed the most to the definition of each component were included in the final multilayer dataset

Zhang J, Zhang M, Zhang WH

Tirzepatide population pharmacokinetics and exposure Schneck 19-study pooled popPK (CL/F 0.061 L/h, half-life 5.4 d, accumulation 1.7x, body-weight covariate +22% at 70 kg / -33% at 120 kg)