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Kelch-like ECH-associated protein 1 (Keap1) regulates the activity of Nrf2 in response to oxidative stress and promotes its degradation in the absence of stress

In contrast, the expression levels of vitamin B3 were lower in BC patients compared to both the healthy control group and the benign breast disease group

Meanwhile, NRF2 activated heme oxygenase-1 (HO-1) expression, which encouraged Fe 2+ buildup in LIP and iron release from hemoglobin, as well as iron apoptosis development

The cancer-specific lncRNA LISR customizes ribosomes to suppress anti-tumour immunity

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