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In addition to pernicious anaemia, some people in the UK dont get enough B12 through their diet alone, particularly those who follow a vegan or vegetarian lifestyle

(2000) Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF