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94,95 In COPD, epithelial to mesenchymal transition (EMT) which is associated with airway remodelling and obliteration is activated by canonical pathways such as TGF-, which induce expression of nuclear transcription factors pSMAD2/3 and reduced inhibitory SMAD6/7 expression

A previous 7T MRS study included FEP subjects with an average of 55 weeks of antipsychotic exposure [54], compared with 6 days of median exposure in our sample

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Moreover, its an unfortunate reality that many sickle cell disease patients are indigent because their condition incapacitates and impoverishes them

Phenolic chemicals must be liberated from the matrix during digestion in an absorbable form (bioaccessible), then absorbed and transported to the bloodstream (bioavailable) to exert their biological action (63)