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Through sacrificial oxidation, 7-DHC produces protective derivatives, such as 3,5-dihydroxycholest-7-en-6-one (DHCEO), which disrupt lipid peroxidation chain reactions and mitigate ferroptosis (Li et al., 2024b)

This was associated with reduced oxidative stress assessed by ROS production and lipid peroxidation (Figure 2B) and decreased production of inflammatory cytokines and TGF- (Figure 2, C and D)