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Retinoic acid is found to enhance tight junction protein expression and reduce bacterial translocation in preclinical sepsis models, potentially mitigating multi-organ dysfunction (Martinez Ramos et al., 2025)

It is prescribed to rebuild depleted stores and repair nerve damage, not for general daily nutrition

However, this is unlikely to uncover higher levels of toxicity than predicted here, as infants have lower hepatic enzymatic activity than adults 19,21,22,30 , leading to lower production of haemolytic metabolites compared to adults or older children