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While the direction from ER to mitochondria is established, whether mitochondrial PA can be rerouted back to the ER and converted into TAG remains an open question

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Finally, given that clinician-driven dose changes were allowed for participants on both IR-Tac and LCPT, some participants may not have been at steady state on day 7 or 14, which may have underestimated t 1/2eff

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