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Dosage: While dosage primarily affects the peak concentration (Cmax) and total exposure (AUC), it can sometimes indirectly influence apparent half-life in a non-linear fashion, especially if metabolic pathways become saturated

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If you are deficient in vitamin B12, improvement in symptoms such as tiredness may begin within days to weeks after starting injections

Endurance Athletes: Those participating in long-duration events can benefit from improved energy metabolism and oxygen delivery