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Early clinical studies are encouraging, but larger trials will be needed to determine if microbiome therapies can meaningfully alter the course of MS beyond the effects of standard immunomodulatory drugs

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Blood samples are obtained by heel stick, spotted on filter paper (903, Whatman GmbH, Dasel, Germany), dried and sent daily by courier to the central newborn screening laboratory

This finding aligns with earlier studies suggesting that the symbiotic effects of beneficial soil microorganisms can enhance the accumulation of unsaturated fatty acids in plant cells, thereby maintaining proper membrane fluidity for required multiple membrane-dependent processes and signalling to regulate stress defence under diverse abiotic stresses [72, 73]

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