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This broad genomic influence suggests mechanisms beyond simple receptor activation, potentially explaining the peptide's diverse cognitive and neuroprotective effects

Recent studies with ASCT2 knockout cells reveal that several compensatory mechanisms compensate for its absence, and that it nonetheless plays a role in tumorigenesis in ways that remain to be elucidated

MATERIALS AND METHODS Strains , reagents , and plasmid constructs

290 In 2017, Npl4, an adaptor of the p97 segregase (also known as VCP), was identified as a molecular target for the tumor-suppressive effects of the DSF/Cu complex

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