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These findings, although obtained from models of oxidative stress and mitochondrial dysfunction rather than in autism models, are highly relevant because they target biological mechanism that are also characteristic of ASD (Sachdeva et al., 2022)

In our studys limitations, we acknowledge the relatively modest sample sizes for African, East Asian, Admixed American/Latino, and Middle Eastern populations, which may hinder the robustness of our GWAS findings in diverse ancestries

Decreased histone methylations, including H3K4me3, H3K79me1, H3K79me2, and H4R3me2, can suppress cancer cell malignancy