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Patients should be reviewed 812 weeks after commencing treatment to assess: Symptomatic improvement, particularly resolution of fatigue and neurological symptoms Haematological response (normalisation of haemoglobin and mean cell volume) Reticulocyte count typically rises within one week, indicating bone marrow response Repeat serum B12 testing is generally not useful after starting parenteral therapy, as levels remain elevated for months

It is widely acknowledged that 20th-century heritage forms a significant layer of history displaying transformation of Englands planning philosophy and culture, accompanied by the emergence of new building types, construction techniques and materials (Twentieth Century Society, 2017)

Your body needs vitamin B12 and plays a role in making new blood cells, such as red blood cells, and for your nervous system to function normally

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