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Glycine exhibits neuroprotective effects in ischemic stroke in rats through the inhibition of M1 microglial polarization via the NF-B p65/HIF-1 signaling pathway

10.1016/j.jnutbio.2012.11.002 74

The monomeric M pro is susceptible to glutathionylation at Cys300, and this leads to inhibition of dimerization and loss of activity

Thiery JP, Acloque H, Huang RY, Nieto MA

the effect on the protein redox state In order to study the changes that take part during the short period when GSH is depleted that is not reversed thereafter, we addressed a kinetic assessment of oxidized and glutathionylated nuclear proteins in DEM treated cells versus control