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Liquid chromatographymass spectrometry (LCMS) analysis of serum from 28 SLE patients identified significant downregulation of L-tryptophan, patuletin, tridecanol, 3,4-dihydroxybenzeneacetic acid, and indoleacrylic acid, alongside upregulated palmitic acid levels compared to healthy controls [45]

10.1080/10717544.2022.2100512 5 ChamundeeswariM.JeslinJ.VermaM

Near-term perspectives: AI and rational design of geroprotective peptides Application of artificial intelligence to peptide design transforms the geroprotective research landscape

Besides, several data showed that using IL-15 in a combined therapeutic vaccine setting could enhance the number of active CTLs in sanctuary sites such as B-cell follicles in lymph nodes.19 Sanctuary sites are the tissues with poor CTL and ART penetration