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This loss of medium spiny neurons is due, in part, to altered BDNF transport that results in a reduction of BDNF release [17, 20]

With 1 mM GABA, the mean POD activity decreased to 28.08 U/g FW, representing a percentage change of -33.17%

Increase compared to control diet, decrease compared to control diet, no significant difference observed compared to control diet

Thus, curcumin increased intracellular ROS levels and inhibited the growth of CML-derived leukemic cells, which was partially rescued by the addition of GSH (Fig

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