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Moreso, enhanced survival of the ERCC mutant cohort in response to ICI administration was observed in comparison with non-mutant ERCC cohorts

European Journal of Clinical Pharmacology, 46(5), 421425

(2) Selectively inhibits voltage-dependent Na + channels, which reduces or stops the release of neurotransmitters and vasoactive peptides, inhibits action potential propagation, and lessens focal discharges (DeLorenzo et al., 2000)

Third, a prospective study has to be conducted for the model (similar to prospective studies for drug candidates), where model predictions are evaluated against the observations made in reality