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Crude Extracts, Flavokawain B and Alpinetin Compounds from the Rhizome of Alpinia mutica Induce Cell Death via UCK2 Enzyme Inhibition and in Turn Reduce 18S rRNA Biosynthesis in HT-29 Cells

Overall, these findings support the careful, targeted use of low-dose isotretinoin in both pre- and post-surgical settings for individuals with thickened or oily nasal skin due to rosacea-related conditions 6 7 8