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Tewari SN, Trembalowicz FC

Researchers have investigated these compounds individually for their potential roles in tissue remodeling, cellular migration, angiogenesis, vascular biology, and wound healing processes

During experiments, DTP cells are primarily identified through in vitro experiments, single-cell sequencing, and flow cytometry

Currently, there are three main strategies for CAF-based immunotherapy: direct CAF depletion, CAF activation and functional suppression, and ECM remodeling limitation induced by CAFs (Fig