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THC exposure has been shown to stimulate the growth of the ER+ MCF-7 cell line (195) and can lead to increased growth and metastasis of tumors with little or no expression of cannabinoid receptors due to suppression of the antitumor immune response (176)

Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence

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Hydrocodone Withdrawal Timeline Clinicians assess withdrawal severity using the Clinical Opiate Withdrawal Scale (COWS), an 11-item instrument scoring pulse rate, diaphoresis, restlessness, pupil size, bone and joint aches, rhinorrhea, GI upset, tremor, yawning, anxiety, and piloerection on a 0 to 47 scale

The physical symptoms can have a slow onset, a rapid onset, and in some cases, may not appear for long periods of time (remission) (3)